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Article

Association analysis of the NrCAM gene in autism and in subsets of families with severe obsessive-compulsive or self-stimulatory behaviors.

Psychiatric genetics - 1 Dec 2006

Sakurai Takeshi, Ramoz Nicolas, Reichert Jennifer G, Corwin Thomas E, Kryzak Lauren, Smith Christopher J, Silverman Jeremy M, Hollander Eric, Buxbaum Joseph D

Abstract excerpt

OBJECTIVES: An autism susceptibility locus (AUTS1, MIM#608636) has been identified in chromosome 7q31. NrCAM is a candidate gene for AUTS1 because it is expressed in the brain and encodes a receptor involved in nervous system development. Polymorphisms in NrCAM have been reported to be associated with autism susceptibility and with substance abuse, implicating NrCAM in reward circuitry. Self-stimulatory,...

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PMID: 17106428
DOI: 10.1097/01.ypg.0000242196.81891.c9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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