Article
An expanded conformation of single-ring GroEL-GroES complex encapsulates an 86 kDa substrate.
Structure (London, England : 1993) - 1 Nov 2006
Chen Dong-Hua, Song Jiu-Li, Chuang David T, Chiu Wah, Ludtke Steven J
Abstract excerpt
Electron cryomicroscopy reveals an unprecedented conformation of the single-ring mutant of GroEL (SR398) bound to GroES in the presence of Mg-ATP. This conformation exhibits a considerable expansion of the folding cavity, with approximately 80% more volume than the X-ray structure of the equivale...
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