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Development and application of an ethically and epidemiologically advantageous assay for the multi-locus microsatellite analysis of Schistosoma mansoni.

Parasitology - 1 Apr 2007

Gower C M, Shrivastava J, Lamberton P H L, Rollinson D, Webster B L, Emery A, Kabatereine N B, Webster J P

Abstract excerpt

Non-availability of adult worms from living hosts remains a key problem in population genetic studies of schistosomes. Indirect sampling involving passage through laboratory animals presents significant ethical and practical drawbacks, and may result in sampling biases such as bottlenecking processes and/or host-induced selection pressures. The novel techniques reported here for sampling, storage and multi-locus...

Topics

Alleles
Animals
Child
Helminth Proteins
Humans
Larva
Microsatellite Repeats
Phylogeny
Polymerase Chain Reaction
Schistosoma mansoni
Schistosomiasis mansoni

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Uganda

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Identifiers

PMID: 17096873
DOI: 10.1017/S0031182006001685
PMCID: PMC2613677

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