Article
Gefitinib efficacy associated with multiple expression of HER family in non-small cell lung cancer.
Anticancer research - 1 Jan 2000
Nishio Makoto, Taguchi Fumiko, Ohyanagi Fumiyoshi, Horikike Atushi, Ishikawa Yuichi, Satoh Yukitoshi, Okumura Sakae, Nakagawa Ken, Nishio Kazuto, Horai Takeshi
Abstract excerpt
UNLABELLED: The aim of this study was to compare the relationship between HER family expression and clinical response to gefitinib. PATIENTS AND METHODS: Tissues from thirty-one non-small cell lung cancer (NSCLC) patients treated with a monotherapy of gefitinib were analyzed. Expressions of HER family in 31 tumors were examined by immunohistochemistry. RESULTS: The total expressions were 21 for EGFR (68%), 24 for...
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