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Article

Conserved expression of alternative splicing variants of peroxisomalacyl-CoA oxidase 1in vertebrates and developmental and nutritional regulation in fish

8 Nov 2006

Abstract excerpt

The acyl-coenzyme A oxidase 1 (ACOX1) catalyzes the first, rate-limiting step in peroxisomal beta-oxidation of medium to very long straight-chain fatty acids. Zebrafish (Danio rerio) acox1 was characterized and compared with homologs from other sequenced genomes, revealing a remarkable conservation of structure in the vertebrate lineage. Strictly conserved regions of the deduced proteins included acyl-CoA oxidase...

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PMID: 17090698
DOI: 10.1152/physiolgenomics.00136.2006

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