Article
CancerGenes: a gene selection resource for cancer genome projects.
Nucleic acids research - 1 Jan 2007
Higgins Maureen E, Claremont Martine, Major John E, Sander Chris, Lash Alex E
Abstract excerpt
The genome sequence framework provided by the human genome project allows us to precisely map human genetic variations in order to study their association with disease and their direct effects on gene function. Since the description of tumor suppressor genes and oncogenes several decades ago, both germ-line variations and somatic mutations have been established to be important in cancer-in terms of risk,...
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