Article
Post-hoc analysis on the CD14 C(-260)T promoter polymorphism and coronary heart disease.
Physiological research - 1 Jan 2007
Porsch-Ozcürümez M, Hucke J, Westphal S, Hubáček J A, Schmitz G, Luley C
Abstract excerpt
Functional C(-260)--> T polymorphism in the promoter of the CD14 gene has been reported to be associated with coronary heart disease (CHD). The functional role of the polymorphism, however, is still a matter of debate, since several studies have not proved its effect on clinical outcomes associated with atherosclerosis. Cardiovascular-related morbidity and mortality was assessed in a post-hoc approach four years...
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