Article
Familial aggregation of insulin resistance and cardiovascular risk factors in hypertension.
Journal of clinical hypertension (Greenwich, Conn.) - 1 Nov 2006
Raji Annaswamy, Williams Jonathan S, Hopkins Paul N, Simonson Donald C, Williams Gordon H
Abstract excerpt
The authors assessed the familial aggregation of cardiometabolic abnormalities (elevated homeostasis model assessment [HOMA], triglycerides [TG], and low-density lipoprotein [LDL] and reduced high-density lipoprotein [HDL]) among hypertensive siblings (N=287 from 138 families). Evidence for familial aggregation required sibling-pair concordance of outcome variables dichotomized according to predefined values...
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