Article
Recent history of artificial outcrossing facilitates whole-genome association mapping in elite inbred crop varieties.
Proceedings of the National Academy of Sciences of the United States of America - 5 Dec 2006
Rostoks Nils, Ramsay Luke, MacKenzie Katrin, Cardle Linda, Bhat Prasanna R, Roose Mikeal L, Svensson Jan T, Stein Nils, Varshney Rajeev K, Marshall David F, Graner Andreas, Close Timothy J, Waugh Robbie
Abstract excerpt
Genomewide association studies depend on the extent of linkage disequilibrium (LD), the number and distribution of markers, and the underlying structure in populations under study. Outbreeding species generally exhibit limited LD, and consequently, a very large number of markers are required for effective whole-genome association genetic scans. In contrast, several of the world's major food crops are...
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