Article
Impact of lipoprotein lipase gene polymorphisms on ulcerative colitis.
World journal of gastroenterology - 21 Oct 2006
Kosaka Toshihito, Yoshino Junji, Inui Kazuo, Wakabayashi Takao, Okushima Kazumu, Kobayashi Takashi, Miyoshi Hironao, Nakamura Yuta, Hayashi Shigekazu, Shiraishi Taizou, Watanabe Masatoshi, Yamamoto Takayuki, Nakahara Ai, Katoh Takahiko
Abstract excerpt
AIM: To examine the influence of lipoprotein lipase (LPL) gene polymorphism in ulcerative colitis (UC) patients. METHODS: Peripheral blood was obtained from 131 patients with UC and 106 healthy controls for DNA extraction. We determined LPL gene polymorphisms affecting the enzyme at Ser447stop, as well as Hind III and Pvu II polymorphisms using PCR techniques. PCR products were characterized by PCR-RFLP and...
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