Article
Cytokeratin 15 can be used to identify the limbal phenotype in normal and diseased ocular surfaces.
Investigative ophthalmology & visual science - 1 Nov 2006
Yoshida Satoru, Shimmura Shigeto, Kawakita Tetsuya, Miyashita Hideyuki, Den Seika, Shimazaki Jun, Tsubota Kazuo
Abstract excerpt
PURPOSE: To elucidate the expression pattern of K15, K19, K14, and K12 in human and mouse ocular surface epithelium as putative markers of epithelial phenotype. METHODS: Immunohistochemical staining with specific antibodies for K15, K19, K14, and K12 was performed in human donor cornea tissue and normal ICR mouse corneas, with emphasis on localization of immunopositive cells. Immunohistochemistry was performed in...
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