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Article

Modular Activation of Nuclear Factor-κB Transcriptional Programs in Human Diabetic Nephropathy

25 Oct 2006

Abstract excerpt

Diabetic nephropathy (DN) is the leading cause of end-stage renal failure and a major risk factor for cardiovascular mortality in diabetic patients. To evaluate the multiple pathogenetic factors implicated in DN, unbiased mRNA expression screening of tubulointerstitial compartments of human renal biopsies was combined with hypothesis-driven pathway analysis. Expression fingerprints obtained from biopsies with...

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Share to Cytokine Signaling Pathways and Interactions
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 17065335
DOI: 10.2337/db06-0477

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