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Identification of transcription factors related to diabetic tubulointerstitial injury

29 Mar 2023

Abstract excerpt

BACKGROUND: Diabetic nephropathy (DN) is a main cause of chronic renal failure. Despite decades of extensive study, the molecular mechanisms underlying diabetic tubulointerstitial injury remain unclear. We aim to identify key transcription factor genes involved in diabetic tubulointerstitial injury. METHODS: A microarray dataset (GSE30122) from Gene Expression Omnibus (GEO) was downloaded. A total of 38...

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PMID: 36978091
DOI: 10.1186/s12967-023-04069-8

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