Article
Intra- and interindividual variation in gene expression in human adipose tissue.
Pflugers Archiv : European journal of physiology - 1 Mar 2007
van Beek Esther A, Bakker Arjen H, Kruyt Philip M, Hofker Marten H, Saris Wim H, Keijer Jaap
Abstract excerpt
Adipose tissue is a highly plastic tissue with an important endocrine and metabolic function. To understand its role in human health and disease, it is necessary to understand the extent of variation and the specific differences within and between different depots and subjects. We employed cDNA microarray analysis to investigate this in human subjects ranging from lean to mildly obese. We observe (1) high...
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