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Article

Risk factors differ for non-small-cell lung cancers with and without EGFR mutation: assessment of smoking and sex by a case-control study in Japanese.

Cancer science - 1 Jan 2007

Matsuo Keitaro, Ito Hidemi, Yatabe Yasushi, Hiraki Akio, Hirose Kaoru, Wakai Kenji, Kosaka Takayuki, Suzuki Takeshi, Tajima Kazuo, Mitsudomi Tetsuya

Abstract excerpt

The present study aimed to assess the impact of smoking and sex for the risk of non-small-cell lung cancer (NSCLC) with or without epidermal growth factor receptor (EGFR) mutation. We conducted a case-control study using 152 patients with EGFR-mutated (EGFRmut) NSCLC, 283 with EGFR-wild-type (EGFRwt) NSCLC and 2175 age- and sex-frequency-matched controls. Smoking was a significant risk factor for EGFRwt NSCLC...

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Identifiers

PMID: 17054433
DOI: 10.1111/j.1349-7006.2006.00347.x
PMCID: PMC11158381

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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