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Article

Assessment of genetic stability of Brucella melitensis Rev 1 vaccine strain by multiple-locus variable-number tandem repeat analysis.

Vaccine - 12 Apr 2007

García-Yoldi David, Le Fleche Philippe, Marín Clara M, De Miguel María J, Muñoz Pilar M, Vergnaud Gilles, López-Goñi Ignacio

Abstract excerpt

The assessment of the genetic stability is one of the essential elements to guarantee the biological quality of live anti-bacteria vaccines. Live attenuated Brucella melitensis Rev 1 is the most effective vaccine against brucellosis in small ruminants. Thirty-six B. melitensis Rev 1 vaccine strains isolated from human or animal sources from different geographic regions, from different commercial batches or...

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Identifiers

PMID: 17050051
DOI: 10.1016/j.vaccine.2006.09.063

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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