Article
Modelling the developmental origins of health and disease in the early embryo.
Theriogenology - 1 Jan 2007
Sinclair Kevin D, Singh Ravinder
Abstract excerpt
The concept that certain adult diseases, such as hypertension, type 2 diabetes and dyslipidaemia can originate from events occurring in utero arose from epidemiological studies in humans but has since been supported by numerous animal-based studies. Referred to as the "developmental origins of health and disease" or "DOHaD" hypothesis, nutritional studies to date have largely focused on two experimental paradigms...
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