Article
[Determination of the phenotype of N-acetyltransferase activity].
Laboratornoe delo - 1 Jan 1990
Bulovskaia L N, Borisenko G N, Drobachenko O A, Kurbatova G P, Ivanova V V
Abstract excerpt
The authors suggest a simple easily reproducible micromethod for determination of genetically determined activity of N-acetyltransferase (EC 2.3.1.5) and acetylator phenotype. The method consists in oral intake of sulfadimezine as an acetylation substrate, followed by measurement of the enzyme activity from the degree of sulfadimezine acetylation in blood or urine samples. Examinations of 121 children with acute...
Topics
- Acetyltransferases
- Adolescent
- Child
- Child, Preschool
- Humans
- Infant
- Phenotype
- Respiratory Tract Infections
- Virus Diseases