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EXPERIMENTAL INFECTION OF THE NEOTROPICAL MALARIA VECTOR ANOPHELES DARLINGI BY HUMAN PATIENT-DERIVED PLASMODIUM VIVAX IN THE PERUVIAN AMAZON

1 Oct 2006

Abstract excerpt

Malaria transmission from humans to mosquitoes is modulated by human host immune factors. Understanding mechanisms by which the human host response may impair parasite infectivity for mosquitoes has direct implications for the development of transmission-blocking vaccines. We hypothesized that despite a low transmission intensity of malaria in the Peruvian Amazon region of Iquitos, transmission-blocking immunity...

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PMID: 17038681
DOI: 10.4269/ajtmh.2006.75.610

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