Article
Bioengineered human corneal endothelium for transplantation.
Archives of ophthalmology (Chicago, Ill. : 1960) - 1 Oct 2006
Lai Jui-Yang, Chen Ko-Hua, Hsu Wen-Ming, Hsiue Ging-Ho, Lee Yen-Hsien
Abstract excerpt
OBJECTIVE: To investigate whether the bioengineered human corneal endothelial cell (HCEC) monolayers harvested from thermoresponsive culture supports could be used as biological tissue equivalents. METHODS: Untransformed adult HCECs derived from eye bank corneas were cultivated on a thermoresponsive poly-N-isopropylacrylamide-grafted surface for 3 weeks at 37 degrees C. Confluent cell cultures with a phenotype...
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