Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Singapore familial adenomatous polyposis (FAP) patients with classical adenomatous polyposis but undetectable APC mutations have accelerated cancer progression.

The American journal of gastroenterology - 1 Dec 2006

Cao Xia, Hong Yi, Eu Kong Weng, Loi Carol, Cheah Peh Yean

Abstract excerpt

OBJECTIVES: Germline mutation in adenomatous polyposis coli (APC) is detected in up to 80% of familial adenomatous polyposis (FAP) patients worldwide. In this study, we evaluated clinical features and APC mutations of Singapore FAP patients and contrasted genotype-phenotype correlation with Cauca...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenomatous Polyposis Coli
Share to Aged
Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms

Share to Genes, APC

Share to Genotype

Share to Germ-Line Mutation

Share to Singapore

Source

Identifiers

PMID: 17026565
DOI: 10.1111/j.1572-0241.2006.00842.x

Genes

APC
FAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17026565-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Singapore familial adenomatous polyposis (FAP) patients with classical adenomatous polyposis but undetectable APC mutations have accelerated cancer progression.PMID 17026565Read ↗

Clinical characteristics and APC gene mutation spectrum of familial adenomatous polyposis patients in ChinaSemantic proximity Read ↗

Clinical characterization and the mutation spectrum in Swedish adenomatous polyposis families.Semantic proximity Read ↗

Genomics of Hereditary Colorectal Cancer: Lessons Learnt from 25 Years of the Singapore Polyposis Registry.Semantic proximity Read ↗

Integrated genotype-phenotype analysis of familial adenomatous polyposis-associated hepatocellular adenomas.Semantic proximity Read ↗

APC mutation and phenotypic spectrum of Singapore familial adenomatous polyposis patients.Semantic proximity Read ↗

Genetic differences in familial adenomatous polyposis syndrome in a Hungarian population: A prospective single center study.Semantic proximity Read ↗

APC or MUTYH mutations account for the majority of clinically well-characterized families with FAP and AFAP phenotype and patients with more than 30 adenomas.Semantic proximity Read ↗

Gardner syndrome in a Tunisian family: Identification of a rare APC mutation through targeted NGS.Semantic proximity Read ↗

Mutation analysis of the APC gene in Taiwanese FAP families: low incidence of APC germline mutation in a distinct subgroup of FAP families.Semantic proximity Read ↗

Familial adenomatous polyposis.Semantic proximity Read ↗

Exome sequencing of familial adenomatous polyposis-like individuals identifies both known and novel causative genes.Semantic proximity Read ↗

Novel and reported APC germline mutations in Chinese patients with familial adenomatous polyposis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.