Article
Lack of association between the platelet glycoprotein Ia C807T gene polymorphism and coronary artery disease: a meta-analysis.
International journal of cardiology - 31 May 2007
Tsantes Argirios E, Nikolopoulos Georgios K, Bagos Pantelis G, Vaiopoulos Georgios, Travlou Anthi
Abstract excerpt
BACKGROUND: The platelet-collagen receptor, glycoprotein (GP) la/lla plays a crucial role in the adhesion of platelets to fibrillar collagen, an event contributing to the pathogenesis of thrombosis. The C807T polymorphism of the GPla gene is considered a genetic marker of the platelet GPla/lla density. The importance of the GPla gene C807T polymorphism as a genetic risk factor for coronary artery disease (CAD)...
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