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Article

Differential expression of WNT4 in testicular and ovarian development in a marsupial

3 Oct 2006

Abstract excerpt

BACKGROUND: WNT4 is a key regulator of gonadal differentiation in humans and mice, playing a pivotal role in early embryogenesis. Using a marsupial, the tammar wallaby, in which most gonadal differentiation occurs after birth whilst the young is in the pouch, we show by quantitative PCR during early testicular and ovarian development that WNT4 is differentially expressed in gonads. RESULTS: Before birth, WNT4...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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Share to Wnt/β-catenin signaling in development and cancer

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PMID: 17014734
DOI: 10.1186/1471-213x-6-44

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