Article
Adaptive response of microglial cells to in vitro infection by Candida albicans isolates with different genomic backgrounds.
Microbial pathogenesis - 1 Dec 2006
Neglia Rachele, Colombari Bruna, Peppoloni Samuele, Orsi Carlotta, Tavanti Arianna, Senesi Sonia, Blasi Elisabetta
Abstract excerpt
It has been recently demonstrated that Candida albicans isolates with distinct genomic backgrounds (namely, b and c genotypes) express different susceptibility to antifungal activity by human monocytes in vitro. We show here that, although comparable in their ability to undergo dimorphic transition and in susceptibility to phagocytosis by microglial cells, the b and c isolates show striking differences in terms...
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