Article
-765G > C COX-2 polymorphism may be a susceptibility marker for gastric adenocarcinoma in patients with atrophy or intestinal metaplasia.
World journal of gastroenterology - 14 Sept 2006
Pereira Carina, Sousa Hugo, Ferreira Paula, Fragoso Maria, Moreira-Dias Luís, Lopes Carlos, Medeiros Rui, Dinis-Ribeiro Mário
Abstract excerpt
AIM: To investigate the relationship between the -765G > C COX-2 polymorphism and the development of different gastric lesions: atrophy or intestinal metaplasia and gastric adenocarcinoma. METHODS: A cross-sectional study was performed involving 320 Portuguese individuals (210 without evidence of neoplastic disease, 73 patients with gastric adenocarcinomas and 37 with atrophy or intestinal metaplasia) using a...
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