Article
Evidence for increased clinical severity of familial and sporadic Paget's disease of bone in Campania, southern Italy.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Dec 2006
Rendina Domenico, Gennari Luigi, De Filippo Gianpaolo, Merlotti Daniela, de Campora Enrico, Fazioli Flavio, Scarano Gioacchino, Nuti Ranuccio, Strazzullo Pasquale, Mossetti Giuseppe
Abstract excerpt
UNLABELLED: The analysis of 236 Italian patients with Paget's bone disease showed higher clinical severity and greater frequency of neoplastic degeneration among patients who live or descend from individuals living in the Campania region (southern Italy). A prevalent involvement of the spine and the skull, the sites preferentially involved in giant cell tumors complicating Paget's disease, was also shown in...
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