Alveolar Soft-part Sarcoma of the Urinary Bladder With Urethral Recurrence: A Unique Case With Emphasis on Differential Diagnoses and Diagnostic Utility of an Immunohistochemical Panel Including TFE3

Abstract excerpt

Alveolar soft-part sarcoma (ASPS) is a rare, clinically, morphologically, ultrastructurally, and cytogenetically distinctive malignant mesenchymal tumor that most classically occurs in the extremities of adolescents and young adults, but has also been described in a number of unusual sites. The molecular signature of ASPS is a specific der(17)t(X;17)(p11.2;q25) translocation, which results in the fusion of TFE3...

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