Article
Identification of OmpU of Vibrio vulnificus as a fibronectin-binding protein and its role in bacterial pathogenesis.
Infection and immunity - 1 Oct 2006
Goo Sung Young, Lee Hyun-Ju, Kim Woo Hwang, Han Kyu-Lee, Park Dae-Kyun, Lee Hyun-Jung, Kim Sung Min, Kim Kun-Soo, Lee Kyu-Ho, Park Soon-Jung
Abstract excerpt
Vibrio vulnificus is a pathogenic bacterium that causes gastroenteritis and primary septicemia. To identify factors involved in microbial adherence to the host cells, we investigated bacterial proteins capable of binding to fibronectin, one of the main components comprised of the extracellular matrix of mammalian cells. A protein of approximately 35 kDa was purified from the extracts of V. vulnificus by its...
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