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Article

High level transcription of the glucocerebrosidase pseudogene in normal subjects and patients with Gaucher disease.

The Journal of clinical investigation - 1 Oct 1990

Sorge J, Gross E, West C, Beutler E

Abstract excerpt

Gaucher disease is due to mutations involving the glucocerebrosidase gene. A closely homologous pseudogene is located approximately 16 kD downstream from the functional gene. Sequence analysis of clones from cDNA libraries made from skin fibroblast cultures showed several independent clones with the sequence of an aberrantly processed pseudogene message. Examination of cellular RNA from lymphoblasts or...

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Identifiers

PMID: 1698821
DOI: 10.1172/JCI114818
PMCID: PMC296842

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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