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Article

The mosaic nature of intergenic 16S-23S rRNA spacer regions suggests rRNA operon copy number variation in Clostridium difficile strains.

Applied and environmental microbiology - 1 Nov 2006

Sadeghifard Nourkhoda, Gürtler Volker, Beer Michael, Seviour Robert J

Abstract excerpt

Clostridium difficile is a major spore-forming environmental pathogen that causes serious health problems in patients undergoing antibiotic therapy. Consequently, reliable and sensitive methods for typing individual strains are required for epidemiological and environmental studies. Ribotyping is generally considered the best method, but it fails to account for sequence diversity which might exist in intergenic...

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Identifiers

PMID: 16980415
DOI: 10.1128/AEM.01179-06
PMCID: PMC1636144

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Source receipt: pubmed, retrieved 7 Sept 2026.

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