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Comment on "Large-scale sequence analysis of avian influenza isolates".

Science (New York, N.Y.) - 15 Sept 2006

Holmes Edward C, Lipman David J, Zamarin Dmitriy, Yewdell Jonathan W

Abstract excerpt

Obenauer et al. (Research Articles, 17 March 2006, p. 1576) reported that the influenza A virus PB1-F2 gene is evolving under strong positive selection, as documented by an extremely high ratio of the number of nonsynonymous nucleotide substitutions to the number of synonymous substitutions (dN/dS). However, we show that this observation is likely to be an artifact related to the location of PB1-F2 in the +1...

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PMID: 16973862
DOI: 10.1126/science.1131729

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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