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Article

Bipolar II and anxious reactive "comorbidity": toward better phenotypic characterization suitable for genotyping.

Journal of affective disorders - 1 Dec 2006

Akiskal Hagop S, Akiskal Kareen K, Perugi Giulio, Toni Cristina, Ruffolo Giuseppe, Tusini Giuseppe

Abstract excerpt

OBJECTIVE: In DSM-IV, bipolar II (BP-II) disorder is defined by depression and hypomania. There is little appreciation of affective instability, often associated with anxiety-particularly panic disorder and agoraphobia (PDA)-comorbidity. This association has genetic-familial implications, which we believe must be incorporated in refining the BP-II phenotype suitable for genotyping purposes. METHOD: We examined in...

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Identifiers

PMID: 16973219
DOI: 10.1016/j.jad.2006.08.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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