Article
T activation marker evaluation in ARC patients treated with AZT. Comparison with CD4+ lymphocyte count in non-progressors and progressors towards AIDS.
Clinical and experimental immunology - 1 Aug 1990
Levacher M, Tallet S, Dazza M C, Dournon E, Rouveix B, Pocidalo J J
Abstract excerpt
Reductions in the percentage and absolute number of CD4+ lymphocytes, as well as abnormally high levels of activated peripheral T lymphocytes (CD3+ HLA-DR+ phenotype) and an increased proportion of CD8+ cells coexpressing the CD57 surface antigen (involved in natural killer activity) have been reported in HIV infection and associated with disease progression. We prospectively measured these subsets of lymphocytes...
Topics
- AIDS-Related Complex
- Acquired Immunodeficiency Syndrome
- Adult
- Antigens, Differentiation, T-Lymphocyte
- CD3 Complex
- CD4 Antigens
- CD4-Positive T-Lymphocytes
- CD57 Antigens
- CD8 Antigens
- Cohort Studies