Article
Sensitivity of basophils to histamine releasing factor(s) of various origin: dependency on allergic phenotype of the donor and surface-bound IgE.
The Journal of allergy and clinical immunology - 1 Jul 1990
Alam R, Forsythe P A, Rankin J A, Boyars M C, Lett-Brown M A, Grant J A
Abstract excerpt
Certain species of histamine-releasing factor (HRF) have been demonstrated to distinguish a select group of allergic patients from healthy subjects. An IgE-dependent mechanism of action has been suggested. The donor and IgE dependency of HRF produced by peripheral blood mononuclear cells (PBMCs)...
Topics
- Asthma
- Basophils
- Biomarkers, Tumor
- Bronchoalveolar Lavage Fluid
- Histamine Release
- Humans
- Hypersensitivity
- Immunoglobulin E
- Lactates
- Lactic Acid
- Lymphokines
- Phenotype
- Skin Tests
- Tumor Protein, Translationally-Controlled 1