Article
Sensitivity of basophils to histamine releasing factor(s) of various origin: dependency on allergic phenotype of the donor and surface-bound IgE.
The Journal of allergy and clinical immunology - 1 Jul 1990
Alam R, Forsythe P A, Rankin J A, Boyars M C, Lett-Brown M A, Grant J A
Abstract excerpt
Certain species of histamine-releasing factor (HRF) have been demonstrated to distinguish a select group of allergic patients from healthy subjects. An IgE-dependent mechanism of action has been suggested. The donor and IgE dependency of HRF produced by peripheral blood mononuclear cells (PBMCs) has not been clearly demonstrated. In this study, we have compared the response of basophils from normal subjects...
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