Bovine gamma globulin-specific CD4+ T cells are retained by bovine gamma-globulin-tolerant mice.

doi:10.1002/eji.1830200612

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Article

Bovine gamma globulin-specific CD4+ T cells are retained by bovine gamma-globulin-tolerant mice.

European journal of immunology - 1 Jun 1990

Burtles S S, Taylor R B, Hooper D C

Abstract excerpt

Immunological tolerance is an acquired state of antigen-specific nonresponsiveness which is generally attributed to either the deletion or suppression of tolerogen-specific T helper cell clones. Unresponsiveness to xenogeneic immunoglobulins can be readily induced and has been extensively studied in order to ascertain the means by which tolerance is established and maintained. As an absence of reactivity to...

Topics

Animals
Antibodies, Anti-Idiotypic
CD4-Positive T-Lymphocytes
Cattle
Immune Tolerance
In Vitro Techniques
Interleukin-2
Lymphocyte Activation
Mice
Mice, Inbred CBA
Phenotype

gamma-Globulins

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