Article
Single, double and triple mutants of Salmonella enterica serovar Typhimurium degP (htrA), degQ (hhoA) and degS (hhoB) have diverse phenotypes on exposure to elevated temperature and their growth in vivo is attenuated to different extents.
Microbial pathogenesis - 1 Jan 2000
Mo Elaine, Peters Sarah E, Willers Chrissie, Maskell Duncan J, Charles Ian G
Abstract excerpt
DegP (HtrA) is a well-studied protease involved in survival of bacteria under stress conditions in vitro and in vivo. There are two paralogues of DegP in the Salmonella enterica serovar Typhimurium genome, DegQ and DegS. In order to understand more about the biological significance of this gene family, a series of deg-deletion mutants was generated in S. Typhimurium strain SL3261 by allelic replacement. At...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.