Prenatal diagnosis of the Cockayne syndrome: survey of 15 years experience

Abstract excerpt

OBJECTIVE: Evaluation of results in a consecutive series of 29 prenatal diagnoses for the Cockayne syndrome. METHODS: Recovery of DNA-synthesis in UV-irradiated cultured fetal cells was measured by scintillation counting of incorporated (3)H-thymidine. Semiquantitative autoradiographic assessment of the recovery of RNA-synthesis (RecRS) was used as an adjunctive method. RESULTS: In 26 of the 29 pregnancies at...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to DNA Repair Mechanisms
• Share to Microtubule and mitosis dynamics
• Share to Prenatal Screening and Diagnostics