Characterization of the repertoire of hypervariable regions in the Protein II (opa) gene family of Neisseria gonorrhoeae.

doi:10.1111/j.1365-2958.1990.tb00610.x

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Article

Characterization of the repertoire of hypervariable regions in the Protein II (opa) gene family of Neisseria gonorrhoeae.

Molecular microbiology - 1 Mar 1990

Connell T D, Shaffer D, Cannon J G

Abstract excerpt

P.II outer membrane proteins of Neisseria gonorrhoeae are encoded by a family of closely related genes. Although the genes are highly conserved, major differences in sequence among them occur in two short regions, designated hypervariable regions 1 (HV1) and 2 (HV2). In this study, we determined...

Topics

Amino Acid Sequence
Antigens, Bacterial
Bacterial Outer Membrane Proteins
Base Sequence
Chromosome Mapping
Cloning, Molecular
DNA, Bacterial
Epitopes
Genetic Variation
Molecular Sequence Data
Multigene Family
Neisseria gonorrhoeae

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