Article
Analysis of sequences and loci of p44 homologs expressed by Anaplasma phagocytophila in acutely infected patients.
Journal of clinical microbiology - 1 Aug 2002
Lin Quan, Zhi Ning, Ohashi Norio, Horowitz Harold W, Aguero-Rosenfeld Maria E, Raffalli John, Wormser Gary P, Rikihisa Yasuko
Abstract excerpt
Anaplasma phagocytophila is an obligatory intragranulocytic bacterium that causes human granulocytic ehrlichiosis. Immunodominant 44-kDa outer membrane proteins of A. phagocytophila are encoded by a p44 multigene family. In the present study, expression profiles of p44 genes in the blood of acutely infected patients in the year 2000 were characterized. A single p44 gene was predominantly expressed in peripheral...
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