Article
Non-cell-autonomous rescue of anaphase-promoting complex function revealed by mosaic analysis of HOBBIT, an Arabidopsis CDC27 homolog.
Proceedings of the National Academy of Sciences of the United States of America - 29 Aug 2006
Serralbo Olivier, Pérez-Pérez José Manuel, Heidstra Renze, Scheres Ben
Abstract excerpt
The Arabidopsis HOBBIT (HBT) gene encodes a homolog of the CDC27 anaphase-promoting complex/cyclosome subunit and is essential for postembryonic development. We induced loss-of-function clones by Cre/lox-mediated recombination of a single complementing HBT transgene in a background homozygous for the strong mutant allele hbt(2311). Defects in cell division and cell expansion are the primary consequences of...
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