Article
SAMBA, a plant-specific anaphase-promoting complex/cyclosome regulator is involved in early development and A-type cyclin stabilization.
Proceedings of the National Academy of Sciences of the United States of America - 21 Aug 2012
Eloy Nubia B, Gonzalez Nathalie, Van Leene Jelle, Maleux Katrien, Vanhaeren Hannes, De Milde Liesbeth, Dhondt Stijn, Vercruysse Leen, Witters Erwin, Mercier Raphaël, Cromer Laurence, Beemster Gerrit T S, Remaut Han, Van Montagu Marc C E, De Jaeger Geert, Ferreira Paulo C G, Inzé Dirk
Abstract excerpt
The anaphase-promoting complex/cyclosome (APC/C) is a large multiprotein E3 ubiquitin ligase involved in ubiquitin-dependent proteolysis of key cell cycle regulatory proteins, including the destruction of mitotic cyclins at the metaphase-to-anaphase transition. Despite its importance, the role of the APC/C in plant cells and the regulation of its activity during cell division remain poorly understood. Here, we...
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