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Article

Lipidomic strategies to study structural and functional defects of ABC-transporters in cellular lipid trafficking.

FEBS letters - 9 Oct 2006

Schmitz Gerd, Liebisch Gerhard, Langmann Thomas

Abstract excerpt

The majority of the human ATP-binding cassette (ABC)-transporters function in cellular lipid trafficking and in the regulation of membrane lipid composition associating their dysfunction with human disease phenotypes related to sterol, phospholipid and fatty acid homeostasis. Based on findings from monogenetic disorders, animal models, and in vitro systems, major clues on the expression, function and cellular...

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PMID: 16934254
DOI: 10.1016/j.febslet.2006.08.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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