Article
Gonococci exit apically and basally from polarized epithelial cells and exhibit dynamic changes in type IV pili.
Cellular microbiology - 1 Sept 2006
Criss Alison K, Seifert H Steven
Abstract excerpt
Type IV pili are a major virulence factor of the obligate human pathogen Neisseria gonorrhoeae (the gonococcus; Gc). Pili facilitate bacterial adherence to epithelial cells, but their participation in later steps of epithelial infection, particularly intracellular replication and exit, is poorly understood. Using polarized T84 cells as a model for mature mucosal epithelia, pilus dynamics in piliated,...
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