Article
5-Azacytidine-resistant mutants of Chlorella virus IL-3A.
Virology - 1 May 1990
Burbank D E, Shields S L, Schuster A M, Van Etten J L
Abstract excerpt
Many dsDNA-containing viruses which infect the unicellular, eukaryotic Chlorella-like green alga strain NC64A encode for DNA methyltransferases and DNA site-specific (restriction) endonucleases. We have hypothesized that these endonucleases help degrade host DNA permitting deoxynucleotides to recycle into virus DNA. This hypothesis was tested by isolating deletion mutants of Chlorella virus IL-3A lacking...
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