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Genetic relationship between placental and fetal weights and markers of the metabolic syndrome in rat recombinant inbred strains.

Physiological genomics - 16 Aug 2006

Buresova Martina, Zidek Vaclav, Musilova Alena, Simakova Miroslava, Fucikova Alena, Bila Vlasta, Kren Vladimir, Kazdova Ludmila, Di Nicolantonio Robert, Pravenec Michal

Abstract excerpt

Epidemiological studies have shown a clear link between fetal growth retardation and an increased propensity for later cardiovascular disease in adults. It has been hypothesized that such early fetal deprivation "programs" individuals toward a life-long metabolical "thrifty phenotype" that predisposes adults to such diseases. Here we test this hypothesis, and its possible genetic basis, in rat recombinant inbred...

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PMID: 16914718
DOI: 10.1152/physiolgenomics.00056.2006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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