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Article

Therapeutic targets in melanoma: map kinase pathway.

Current oncology reports - 1 Sept 2006

Haluska Frank G, Ibrahim Nageatte

Abstract excerpt

Recent progress in our understanding of the genetic alterations that occur in the pathogenesis of melanoma provides exciting opportunities for therapy. The most important signaling pathways in melanoma lie downstream of NRAS: the RAS-BRAF-MAPK pathway. A great deal of attention has been focused o...

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Topics

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Share to Drug Therapy, Combination
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Protein Kinase Inhibitors

Share to Proto-Oncogene Proteins B-raf

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Source

Identifiers

PMID: 16901402
DOI: 10.1007/s11912-006-0065-x

Genes

BRAF
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16901402-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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