Article
Isolation and characterization of an expressed hypervariable gene coding for a breast-cancer-associated antigen.
Gene - 14 Sept 1990
Tsarfaty I, Hareuveni M, Horev J, Zaretsky J, Weiss M, Jeltsch J M, Garnier J M, Lathe R, Keydar I, Wreschner D H
Abstract excerpt
A human gene and cDNA coding for a breast-cancer-associated antigen (H23Ag) were isolated and characterized. The gene contains two exons and one intron. Part of the second exon is a tandem repeat array (TRA) consisting of multiple 60-bp G + C-rich units. We report here the characterization of uni...
Topics
- Amino Acid Sequence
- Antigens, Neoplasm
- Base Sequence
- Breast Neoplasms
- Consensus Sequence
- DNA
- Genetic Variation
- Humans
- Introns
- Membrane Glycoproteins
- Molecular Sequence Data
- Mucin-1
- Mucins
- Neoplasm Proteins
- Repetitive Sequences, Nucleic Acid