Article
Isolation and characterization of an expressed hypervariable gene coding for a breast-cancer-associated antigen.
Gene - 14 Sept 1990
Tsarfaty I, Hareuveni M, Horev J, Zaretsky J, Weiss M, Jeltsch J M, Garnier J M, Lathe R, Keydar I, Wreschner D H
Abstract excerpt
A human gene and cDNA coding for a breast-cancer-associated antigen (H23Ag) were isolated and characterized. The gene contains two exons and one intron. Part of the second exon is a tandem repeat array (TRA) consisting of multiple 60-bp G + C-rich units. We report here the characterization of unique sequences that are found in the H23Ag gene and cDNA, in addition to the 60-bp repeats. Analysis of the cDNA...
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