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Article

In vivo selection of OmpK35-deficient mutant after cefuroxime therapy for primary liver abscess caused by Klebsiella pneumoniae.

The Journal of antimicrobial chemotherapy - 1 Oct 2006

Lee Chen-Hsiang, Chia Ju-Hsin, Chu Chishih, Wu Tsu-Lan, Liu Jien-Wei, Su Lin-Hui

Abstract excerpt

OBJECTIVES: The aim of the study was to characterize the genetic basis of beta-lactam resistance developed in clinical isolates of Klebsiella pneumoniae after exposure to cefuroxime. METHODS: Clinical features of two episodes of liver abscess caused by K. pneumoniae in a diabetic patient were reported. Four isolates (KP(1)/KP(2) and KP(3)/KP(4)) of K. pneumoniae were recovered from cultures of blood/pus in the...

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PMID: 16880175
DOI: 10.1093/jac/dkl308

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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