Article
Phenotypic variability in isodicentric Y patients: study of nine cases.
Clinical genetics - 1 Aug 2006
DesGroseilliers M, Beaulieu Bergeron M, Brochu P, Lemyre E, Lemieux N
Abstract excerpt
Isodicentric chromosomes are the most commonly reported aberrations of the human Y chromosome. As they are unstable during cell division and can generate various types of cell lines, most reported patients are chromosomal mosaics, generally including a 45,X cell line. Phenotypes depend on the location of the breakpoints as well as on the proportion of each cell line and vary from male to abnormal female or...
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