Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Isodicentric Y chromosomes in Egyptian patients with disorders of sex development (DSD).

American journal of medical genetics. Part A - 1 Jul 2012

Mekkawy Mona, Kamel Alaa, El-Ruby Mona, Mohamed Amal, Essawi Mona, Soliman Hala, Dessouky Nabil, Shehab Marwa, Mazen Inas

Abstract excerpt

Isodicentric chromosome formation is the most common structural abnormality of the Y chromosome. As dicentrics are mitotically unstable, they are subsequently lost during cell division resulting in mosaicism with a 45,X cell line. We report on six patients with variable signs of disorders of sex development (DSD) including ambiguous genitalia, short stature, primary amenorrhea, and male infertility with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Banding
Share to Chromosomes, Human, Y

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Disorders of Sex Development

Share to In Situ Hybridization, Fluorescence

Share to Infant

Share to Karyotype

Share to Sex Chromosome Aberrations

Source

Identifiers

PMID: 22628100
DOI: 10.1002/ajmg.a.35487

Genes

SRY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Isodicentric Y chromosomes in Egyptian patients with disorders of sex development (DSD).PMID 22628100Read ↗

Cytogenetic Spectrum of Ovotesticular Difference of Sex Development (OT DSD) among a Large Cohort of DSD Patients and Literature ReviewSemantic proximity Read ↗

Molecular and Clinical Characteristics of 26 Cases with Structural Y Chromosome AberrationsSemantic proximity Read ↗

Delineating the association between isodicentric chromosome Y and infertility: a retrospective study.Semantic proximity Read ↗

Phenotypic variability in isodicentric Y patients: study of nine cases.Semantic proximity Read ↗

Short stature as the only presenting feature in a patient with an isodicentric (Y)(q11.23) and gonadoblastoma. A clinical and molecular cytogenetic study.Semantic proximity Read ↗

Disorders of sex development: Genetic characterization of a patient cohortSemantic proximity Read ↗

Advances in genomic diagnosis of a large cohort of Egyptian patients with disorders of sex development.Semantic proximity Read ↗

Uniparental Disomy in Somatic Mosaicism 45,X/46,XY/46,XX Associated with Ambiguous Genitalia.Semantic proximity Read ↗

Hypospadias in a male infant with an unusual mosaic 45,X/46,X,psu idic(Y)(p11.32)/46,XY and haploinsufficiency of SHOX: A case report.Semantic proximity Read ↗

Cytogenetic and molecular characterization of two isodicentric Y chromosomes.Semantic proximity Read ↗

Testicular differentiation in 46,XX DSD: an overview of genetic causesSemantic proximity Read ↗

[Dicentric Y chromosome].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.